abstract：:Purpose: The purpose of this study is to explore the effects of dihydrotestosterone (DHT) on lipopolysaccharide (LPS)-induced proinflammatory cytokine release in human ocular surface epithelial cells exposed to LPS and LPS-binding protein (LBP).Methods: Immortalized human corneal, conjunctival, and meibomian gland epi...

journal_title：Ocular immunology and inflammation

authors： Marangoz D,Oner C,Schicht M,Turgut Cosan D,Paulsen F,Yildiz E,Zibandeh N,Sahin A

更新日期：2019-11-18 00:00:00

abstract：:Aims: To evaluate associations between vision-related (VR-) and health-related (HR-) QoL metrics and inflammation and treatment in non-acute VKHD patients.Methods: Cross-sectional study in a tertiary center in Sao Paulo, Brazil with 22 patients with non-acute VKHD followed prospectively for ≥12 months since acute dise...

journal_title：Ocular immunology and inflammation

authors： Souto FMS,Missaka RFBG,Magalhães BM,Caetano VMC,Takiuti JT,Lavezzo MM,Sakata VM,Oyamada MK,Hirata CE,Yamamoto JH

更新日期：2019-10-31 00:00:00

abstract：:Purpose: To evaluate neurosyphilis cerebrospinal fluid (CSF) findings and initial ophthalmic manifestations in patients with syphilitic uveitis. Methods: We retrospectively reviewed the records of CSF analysis of 14 patients with syphilitic uveitis with treponemal analysis - chemiluminescent immunoassay and TPHA- and ...

journal_title：Ocular immunology and inflammation

authors： Bazewicz M,Lhoir S,Makhoul D,Libois A,Van den Wijngaert S,Caspers L,Willermain F

更新日期：2019-10-24 00:00:00

abstract：:Objective: To report the clinical features and treatment outcomes in immunocompetent patients with anterior segment inflammation (ASI) related to human cytomegalovirus (HCMV) depending on their ethnic origin. Material and Methods: Multicenter retrospective study of 38 patients with at least one test, either HCMV-posit...

journal_title：Ocular immunology and inflammation

authors： Leleu I,Jhanji V,Touhami S,Westcott M,Angi M,Titah C,Rousseau A,Hamard P,Brasnu E,Manicom T,Blumen-Ohana E,Rozenberg F,Vauloup-Fellous C,Deback C,Labetoulle M,Sahel JA,Bodaghi B,Merabet L,Kobal A,Brignole-Baudouin F

更新日期：2019-10-23 00:00:00

abstract：:Purpose: To report a case of cystoid macular edema (CME) secondary to juvenile idiopathic arthritis (JIA)-associated uveitis. Case report: 26-year-old female patient presented with CME in both eyes. CME became refractory and TCZ-IV was initiated. After 12 infusions was stopped because grade 1 neuropenia developed. On ...

journal_title：Ocular immunology and inflammation

authors： Adán A,Moll-Udina A,Ramirez J,Llorenç V

更新日期：2019-10-07 00:00:00

abstract：:Background: Rapid and timely diagnosis of tubercular uveitis (TBU) is of paramount importance to save these eyes from blindness. The present study was, therefore, undertaken to carry out a comparative evaluation of Gene Xpert MTB/RIF (Xpert), MTBDRplus and Multiplex PCR (MPCR) for the diagnosis of TBU. These tests wer...

journal_title：Ocular immunology and inflammation

authors： Sharma K,Gupta A,Sharma M,Sharma A,Bansal R,Sharma SP,Singh RD,Gupta V

更新日期：2019-10-03 00:00:00

abstract：:Purpose: To describe the distinguishing features of retinitis-like lesions seen in vitreoretinal lymphoma (VRL) from viral and toxoplasma retinitis. Methods: In this multicenter, retrospective study, we reviewed charts and imaging of consecutive patients with VRL. The associated features and the characteristics of ret...

journal_title：Ocular immunology and inflammation

authors： Marchese A,Agarwal A,Miserocchi E,Giuffrè C,Bandello F,Modorati G,Prakash G,Gupta N,Bosello F,Sharma SP,Gupta V

更新日期：2019-09-30 00:00:00

abstract：PURPOSE:Relapsing ocular inflammation occurs in about 70% of patients with Behçet's disease (BD) and can lead to permanent loss of vision. Neovascularization of the optic disc (NVD) or elsewhere in the retina (NVE) is a relatively uncommon but severe complication that lacks standardized treatment. METHODS:We report on...

journal_title：Ocular immunology and inflammation

authors： Markomichelakis NN,Aissopou EK,Maselos S,Tugal-Tutkun I,Sfikakis PP

更新日期：2019-01-01 00:00:00

abstract：:Purpose: The purpose of the article is to describe a novel case of idiopathic central nervous system inflammatory disease with bilateral human leukocyte antigen (HLA)-B27-positive anterior uveitis. Methods/Results: A 15-year-old African American boy with bilateral HLA-B27-positive anterior uveitis controlled with topi...

journal_title：Ocular immunology and inflammation

authors： Crowell EL,Pfeiffer ML,Kamdar AA,Koenig MK,Wittenberg SE,Supsupin EP,Adesina OO

更新日期：2019-01-01 00:00:00

abstract：:Purpose: The purpose of the study is to quantify aqueous flare using laser flare photometry (LFM) in patients undergoing 25-G pars plana vitrectomy (PPV) and assess the need for postoperative topical corticosteroid administration . Methods: Prospective evaluation of 50 eyes (50 patients) was performed using LFM until ...

journal_title：Ocular immunology and inflammation

authors： Agarwal A,Joshi D,Katoch D,Aggarwal K,Singh R,Gupta V

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To describe tuberculous uveitis (TU) presenting as a bullous retinal detachment (RD) and to perform a comprehensive literature review on TU with similar features. Methods: Observational case report and systematic literature review. Results: An 84-year-old woman presented with bilateral granulomatous uveitis a...

journal_title：Ocular immunology and inflammation

authors： Song JH,Koreishi AF,Goldstein DA

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To summarize the characteristics of endogenous fungal endophthalmitis (EFE) after genitourinary procedures. Methods: Medical records of patients diagnosed with EFE after genitourinary procedures from a single center during a 6-year period were reviewed. Results: Nineteen eyes of 15 patients were included. The...

journal_title：Ocular immunology and inflammation

authors： Lei B,Jiang R,Gu R,Xu G,Song F,Zhou M

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To analyse the association between skin score with corneal biomechanics and dry eye tests in systemic sclerosis (SSc). Methods: 112 cases (limited SSc (lcSSc), n=50; diffuse SSc  (dcSSc), n=32; controls, n=30) were included in the study. Corneal hysteresis (CH), corneal resistance factor (CRF), Schirmer 1, 2 ...

journal_title：Ocular immunology and inflammation

authors： Ayhan Z,Kaya M,Ozturk T,Arikan G,Birlik M

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To review early withdrawal of immunomodulatory therapy (IMT) for birdshot retinochoroidopathy (BSRC). Design: Retrospective case-series of sixteen patients with Human-leukocyte-antigen-A29-positive BSRC treated with IMT ≥ 1 year and discontinued prior to achieving durable remission, observed ≥ 6 months off IM...

journal_title：Ocular immunology and inflammation

authors： You C,Meese H,Stephenson A,Montieth A,Ma L,Hernandez M,Kubaisi B,Syeda S,Foster CS

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To analyze the clinical features and long-term prognosis of uveitis in tubulointerstitial nephritis and uveitis (TINU) syndrome in a cohort of Chinese patients. Methods: A total of 32 patients with TINU syndrome between 2000 - 2016 were analyzed retrospectively. Results: Mild anterior inflammation was observe...

journal_title：Ocular immunology and inflammation

authors： Yang M,Chi Y,Guo C,Huang J,Yang L,Yang L

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To investigate the prevalence of macular abnormalities in Chinese Vogt-Koyanagi-Harada (VKH) patients.Methods: Clinical characteristics, therapeutic effectiveness and visual outcome were reviewed and analyzed.Results: The most common macular abnormality was macular edema (ME), followed by macular choroidal ne...

journal_title：Ocular immunology and inflammation

authors： Yang P,Ye Z,Xu J,Du L,Zhou Q,Qi J,Liang L,Wang C,Zhou C,Cao Q,Wu L,Kijlstra A

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To compare toll-like receptors 2 (TLR2) and 4 (TLR4) expression in cells of corneal and conjunctival epithelium between unilateral KC patients and control subjects. Methods: Prospective cross-sectional case-control study, including 50 unilateral KC patients and 20 control subjects. TLR2 and TLR4 expression wa...

journal_title：Ocular immunology and inflammation

authors： Malfeito M,Regueiro U,Pérez-Mato M,Campos F,Sobrino T,Lema I

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To investigate the prevalence and characteristics of ocular manifestations of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in patients treated at a tertiary referral center in Taiwan during a time of highly active antiretroviral therapy (HAART) Materials and Methods: A retrospect...

journal_title：Ocular immunology and inflammation

authors： Tsen CL,Chen YS,Wu KS,Tsai HC,Chen YH,Lee YY,Sheu SJ

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To investigate whether variants in the ARMC9 gene encoding KU-MEL-1 are associated with Vogt-Koyanagi-Harada (VKH) disease in a Japanese population. Methods: We recruited 380 Japanese patients with VKH disease and 744 Japanese healthy controls to genotype seven single-nucleotide polymorphisms (SNPs) in ARMC9....

journal_title：Ocular immunology and inflammation

authors： Ohno T,Meguro A,Takeuchi M,Yamane T,Teshigawara T,Kitaichi N,Horie Y,Namba K,Ohno S,Nakao K,Sakamoto T,Sakai T,Nakano T,Keino H,Okada AA,Takeda A,Fukuhara T,Mashimo H,Ohguro N,Oono S,Enaida H,Okinami S,Mizuki

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To evaluate the 10-year drug retention rate of infliximab (IFX) in Behçet's disease (BD)-related uveitis, the effect of a concomitant use of disease modifying anti-rheumatic drugs (DMARDs) on drug survival and differences according to the lines of biologic treatment. METHODS:Cumulative survival rates were stud...

journal_title：Ocular immunology and inflammation

authors： Fabiani C,Sota J,Vitale A,Emmi G,Vannozzi L,Bacherini D,Lopalco G,Guerriero S,Venerito V,Orlando I,Franceschini R,Fusco F,Frediani B,Galeazzi M,Iannone F,Tosi GM,Cantarini L

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To compare genetic testing for microbes in infectious endophthalmitis or uveitis to culture.Methods: This was a retrospective, single-center case series that enrolled patients with clinically suspected endophthalmitis or uveitis of unknown etiology. Aqueous humor or vitreous was collected and sent for routine...

journal_title：Ocular immunology and inflammation

authors： Sandhu HS,Hajrasouliha A,Kaplan HJ,Wang W

更新日期：2019-01-01 00:00:00

abstract：:Increasing resistance to antimicrobial agents has contributed to an elevated risk of complications of infectious keratitis. Corneal collagen cross-linking (CXL) has been widely adopted for the management of keratoconus and post-refractive surgery corneal ectasia. It has recently been introduced as an option for treati...

journal_title：Ocular immunology and inflammation

authors： Bonzano C,Di Zazzo A,Barabino S,Coco G,Traverso CE

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To evaluate multimodal imaging findings in longitudinal follow-up of a patient with presumed tuberculous serpiginous-like choroiditis (TB-SLC). Method: We evaluated multimodal imaging in a 62-year-old male with TB-SLC. Correlation between optical coherence tomography angiography (OCTA), swept-source OCT (SS-O...

journal_title：Ocular immunology and inflammation

authors： Wang H,Tan SZ,Aslam T,Jones NP,Steeples LR

更新日期：2019-01-01 00:00:00

abstract：:Background: Post-streptococcal uveitis is a rare ocular disease which is part of other auto-immune conditions associated with post-streptococcal syndrome. It was first mentioned in medical literature in 1991, with only a few cases published at that time. We are presenting the case of a patient with bilateral panuveiti...

journal_title：Ocular immunology and inflammation

authors： Medina CA,Fajardo A,Calderon A,Aracena M

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To describe with multimodal imaging a case of post-infectious unilateral outer retinopathy with choroiditis. Methods: Retrospective chart review of a case of a 67-year old male who presented following the onset of viral symptoms with an acute onset outer retinopathy, small vessel leakage on fluorescein angiog...

journal_title：Ocular immunology and inflammation

authors： Kodati S,Gangaputra S,Sen HN

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To compare the clinical characteristics of patients with active episodes of ocular toxoplasmosis from three provinces, Misiones, Santa Fe, and Buenos Aires, Argentina. Methods: Patients with a diagnosis of ocular toxoplasmosis from three databases of four tertiary referral uveitis centers were reviewed. Colle...

journal_title：Ocular immunology and inflammation

authors： Schlaen A,Colombero D,Ormaechea S,Ladeveze E,Rudzinski C,Ingolotti M,Couto C,Rudzinski M

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To assess changes in aqueous humor (AH) levels of cytokines following dexamethasone intravitreal implant (DEX) injection for diabetic macular edema (DME).Methods: Sixteen DME and cataract cases series study. Anterior chamber AH sampling was performed at baseline at DEX injection time (T1), cataract surgery 8 ...

journal_title：Ocular immunology and inflammation

authors： Figueras-Roca M,Sala-Puigdollers A,Alforja S,Torras J,Peraza-Nieves J,Zarranz-Ventura J,Adan Civera A,Molins B

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To study outcome of secondary glaucoma in pediatric uveitis patients. Methods: Retrospective analysis of records of uveitis patients ≤16 years. Results: Of 182 pediatric uveitis patients, secondary glaucoma was seen in 48 patients (75 eyes, 26.23%) with female preponderance (F:M-29:19) . JIA was the most comm...

journal_title：Ocular immunology and inflammation

authors： Gautam Seth N,Yangzes S,Thattaruthody F,Singh R,Bansal R,Raj S,Kaushik S,Gupta V,Pandav SS,Ram J,Gupta A

更新日期：2019-01-01 00:00:00

abstract：:Purpose: Corneal involvement in systemic sclerosis (SSc) is rare, but due to rich collagen composition cornea is especially vulnerable to connective tissue diseases. Therefore, our aim was to evaluate corneal parameters of SSc patients. Methods: The study included 32 SSc patients and 39 control subjects with no ocular...

journal_title：Ocular immunology and inflammation

authors： Nagy A,Rentka A,Nemeth G,Ziad H,Szücs G,Szekanecz Z,Gesztelyi R,Zsuga J,Aszalos Z,Szodoray P,Kemeny-Beke A

更新日期：2019-01-01 00:00:00

abstract：:Purpose: To emphasize the different manifestations of ocular involvement in Whipple disease with challenge in establishing the diagnosis as clinical, laboratory, and histological features could mimic other uveitis entities. Methods: Case reports of three patients. Results: The first patient was an African male sufferi...

journal_title：Ocular immunology and inflammation

authors： Testi I,Tognon MS,Gupta V

更新日期：2019-01-01 00:00:00

abstract：:Purpose:: Fungal endophthalmitis following pars plana vitrectomy with silicone oil tamponade is an infrequent entity. Filamentous fungi like aspergillus are generally associated with endophthalmitis. Mucor is a rarely implicated pathogen in cases of endophthalmitis with only two reported cases in medical literature. B...

journal_title：Ocular immunology and inflammation

authors： Dogra M,Bhutani G,Gupta V

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To evaluate the clinical outcome and safety of adalimumab in patients with Vogt-Koyanagi-Harada (VKH) disease. METHODS:VKH patients treated with adalimumab seen at the University of Buenos Aires were reviewed. Main outcome measures were visual acuity, anterior segment inflammation, optic nerve inflammation (ON...

journal_title：Ocular immunology and inflammation

authors： Couto C,Schlaen A,Frick M,Khoury M,Lopez M,Hurtado E,Goldstein D

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:The authors report a case of a 60-year-old Caucasian male with a background of treated Chronic Lymphocytic Leukaemia (CLL) with secondary hypogammaglobulinaemia present with toxoplasma chorioretinitis and negative serum toxoplasma serology on presentation and on subsequent reactivation. METHODS:Retrospective c...

journal_title：Ocular immunology and inflammation

authors： Rajput R,Denniston AK,Murray PI

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:Investigate the efficacy of intravitreal adalimumab in breakthrough panuveitis in patients on systemic adalimumab for more than 3 months. METHODS:Retrospective study of patients on systemic adalimumab with breakthrough panuveitis requiring intravitreal adalimumab therapy. RESULTS:Seven eyes of four patients w...

journal_title：Ocular immunology and inflammation

authors： Kheir WJ,Mehanna CJ,Abdul Fattah M,Al Ghadban S,El Sabban M,Mansour AM,Hamam RN

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To describe treatment practices for ocular toxoplasmosis among members of the Brazilian Uveitis Society. METHODS:An online questionnaire sent to specialists, between October 2014 and March 2015. RESULTS:Most respondents (67.9%) treat all active cases. Most specialists consider visual acuity <20/200 (88.2%), s...

journal_title：Ocular immunology and inflammation

authors： Morais FB,Arantes TEFE,Muccioli C

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To analyze the diagnostic predictive ability of clinical variables. METHODS:Demographic and clinical variables of 172 serologically proven leptospiral uveitis patients were compared with 200 controls of non-leptospiral uveitis. Multiple logistic regression analysis identified diagnostic predictors. A receiver ...

journal_title：Ocular immunology and inflammation

authors： Sivakumar R,Balakrishnan V,Gowri P,Visalakshi J

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To analyze the clinical features, course, management, and outcomes of tubercular (TB) uveitis in the pediatric population and assess the response to anti-tubercular therapy (ATT). METHODS:Hospital records of children (≤16 years) from a large tertiary-care institute between January 2001 and December 2015 were r...

journal_title：Ocular immunology and inflammation

authors： Kaur S,Aggarwal K,Agarwal A,Suri D,Gupta A,Singh R,Bansal R,Singh S,Singh N,Gupta A,Gupta V

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. METHODS:A critical review of literature was performed. RESULTS:Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, severe presentations, and ...

journal_title：Ocular immunology and inflammation

authors： de-la-Torre A

更新日期：2018-01-01 00:00:00

abstract：:Herpes simplex virus, varicella zoster virus, human cytomegalovirus, and rubella virus are the most common causes of virus-induced anterior uveitis. They can present in a variety of entities not only with typical but also overlapping clinical characteristics. These viral infections are commonly associated with ocular ...

journal_title：Ocular immunology and inflammation

authors： De Groot-Mijnes JDF,Chan ASY,Chee SP,Verjans GMGM

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To compare QuantiFERON®-TB Gold and tuberculin skin testing as diagnostic tests for intraocular tuberculosis in HIV positive and negative patients. METHODS:A prospective study evaluating two different tests to help diagnose intraocular tuberculosis. RESULTS:Thirty-five of 106 patients (33.0%) were diagnosed w...

journal_title：Ocular immunology and inflammation

authors： Smit DP,Esterhuizen TM,Meyer D

更新日期：2018-01-01 00:00:00